Porcine epidemic diarrhea (PED) was first reported in the United Kingdom in 1971. The disease was characterized by severe enteritis, vomiting, watery diarrhea, dehydration, and a high mortality rate among swine. Wageningen Bioveterinary Research conducts research on this disease.
The causative agent is porcine epidemic diarrhea virus (PEDV), which belongs to the family of Coronaviridae. It is an enveloped single-stranded positive sense RNA virus.
Spread of porcine epidemic diarrhea
PEDV has been reported in many countries in Europe between 1971 and 1980 and more recently also in Asian countries including China, South Korea, Thailand and Vietnam. The virus was first reported in the USA in May 2013 where it caused a huge outbreak with millions of fatalities in young piglets. In the first half of 2014 outbreaks of PEDV were also reported from Canada and Japan.
The virus is transmitted faecal-orally and may be transmitted by aerosols. Pigs shed virus for 7 -9 days and the virus can be stable in faeces for quite some time.
Good hygiene is essential to prevent infections or to eliminate the virus from a farm. The most important infection routes of PED are animal transport, transport of infected piglets, visitors on the farm and transport of manure. In principle, many well-known disinfectants can be used to control the PED virus, but oxidative disinfectants such as hydrogen peroxide are generally the most effective.
Rapid host response to an infection with Coronavirus. Study of transcriptional responses with Porcine Epidemic Diarrhea Virus: BioRxiv - p.
Inter-laboratory study to characterize the detection of serum antibodies against porcine epidemic diarrhoea virusVeterinary Microbiology 197 (2016). - ISSN 0378-1135 - p. 151 - 160.
Outbreak of Porcine Epidemic Diarrhea Virus in Portugal, 2015Transboundary and Emerging Diseases 62 (2015)6. - ISSN 1865-1674 - p. 586 - 588.
Comparison of two methods for detection of transmissible gastroenteritis virus in feces of pigs with experimentally induced infectionAmerican Journal of Veterinary Research 49 (1988)11. - ISSN 0002-9645 - p. 1836 - 1843.