Systems and Synthetic Biology
The Laboratory of Systems and Synthetic Biology (SSB) contributes to elucidate mechanisms underlying basic cellular processes, evolution and interactions among microbes and between microbes and their environment (including the human host). We do so in the context of entire biological systems. We translate the acquired knowledge into biotechnological, medical and environmental applications.
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Education
Systems and Synthetic Biology teaches several courses and is involved in iGEM. We also facilitate internships and theses for bachelor and master students.
Recent publications
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ReScribe: An Unrestrained Tool Combining Multiplex Recombineering and Minimal-PAM ScCas9 for Genome Recoding Pseudomonas putida
ACS synthetic biology 10 (2021)10. - ISSN 2161-5063 - p. 2672 - 2688. -
Discriminatory plasma biomarkers predict specific clinical phenotypes of necrotizing soft-tissue infections
The Journal of Clinical Investigation 131 (2021)14. - ISSN 0021-9738 -
Model reduction of genome-scale metabolic models as a basis for targeted kinetic models
Metabolic Engineering 64 (2021). - ISSN 1096-7176 - p. 74 - 84.