Diet is an important determinant of a cluster of cardiometabolic risk factors what is generally called the Metabolic Syndrome. This cluster includes abdominal obesity, such as measured by elevated waist circumference, high glucose levels, high triglyceride levels and low HDL-cholesterol concentrations, and elevated blood pressure. Persons with Metabolic Syndrome are at increased risk of developing type diabetes and cardiovascular disease.
The topic Nutrition, obesity and metabolic syndrome at the Division of Human Nutrition and Health of Wageningen University is studied using various study designs and methods. Regarding the etiology we use prospective cohort studies as well as human intervention studies. The role several nutrients, foods and dietary patterns on the Metabolic Syndrome and its underlying risk factor insulin resistance are being studied. In addition, the topic is also addressed from a public health point of view, in the Netherlands as well as in the developing countries. This includes studies on the prevention of weight gain and development of type 2 diabetes in the general community.