Germacrene a synthase mutants

Bosch, Hendrik Jan; Both, Michiel Theodoor Jan De; Cankar, Katarina; Bundock, Paul; Sevenier, Robert Edouard; Beekwilder, Martinus Julius


The invention is in the field of agriculture, in particular in the field of crop improvement for processing, more particularly in the field of sesquiterpene lactone (STL), squalene and phenolic compound biosynthesis by plants. A method for producing a plant having reduced STL levels, increased squalene levels and increased phenolic compound levels is disclosed, as well as a plant produced by such method.