This group focuses on investigating and exploiting genetic variation and biodiversity. It develops and employs various genetic and genomic technologies (including motif directed profiling) to assess biodiversity between and within species, focusing on genetic variation at the allelic level.
Developing technologies for high throughput analysis is another point of attention. Structure and inheritance of the genetic variation is studied using genetic marker maps and through haplotype reconstruction. The study of neutral genetic variation is used in phylogenetic studies and for quantification of dispersal and gene flow.
Key focus area's
The study of functional diversity includes allelic variation for various quality and resistance traits and for the occurrence of allergens (PR10 proteins in apple and birch, gluten protein families in wheat).
Breeding for varieties with reduced allergenicity
In the Western society, prevalence and severity of allergies are rapidly increasing. Our research focus is on solutions for allergy-related matters in the pre-medical stage. We study the diversity of allergens in germplasm, and develop strategies to lower the amount of allergens by breeding. In this way we aim to prevent rather than cure.
Onderzoek essentaksterfte: verschillen in gevoeligheid tussen essen aangetoond
Diblock and random antifouling bioactive polymer brushes on gold surfaces by visible-light-induced polymerization (SI-PET-RAFT) in waterAdvanced Material Interfaces 9 (2022)3. - ISSN 2196-7350
Breeding Late Blight Resistant Potatoes for Organic Farming—a Collaborative Model of Participatory Plant Breeding: the Bioimpuls ProjectPotato Research 65 (2022)2. - ISSN 0014-3065 - p. 349 - 377.
Start derde fase BioimpulsStart derde fase Bioimpuls, Ekoland, 2021-06-01, Leen Janmaat
Work in Progress to fight late BlightWork in Progress to fight late Blight, Prophyta , 2021-11-01, Roger Saats
Participatory potato breeding in the Netherlands
Detecting quantitative trait loci and exploring chromosomal pairing in autopolyploids using polyqtlRBioinformatics 37 (2021)21. - ISSN 1367-4803 - p. 3822 - 3829.
Low Gluten and Coeliac-Safe Wheat through Gene EditingIn: Plant Biotechnology / , Ricroch, A., Chopra, S., Kuntz, M.. - Cham : Springer (Plant Biotechnology ) - ISBN 9783030683443 - p. 231 - 248.
The effect of polarity on the molecular exchange dynamics in imine-based covalent adaptable networksPolymer Chemistry 12 (2021)11. - ISSN 1759-9954 - p. 1635 - 1642.
Development of a new tool (4TREE) for adapted genome selection in European tree species
- Johan Willemsen
- Manos Domazakis
- Aurelie Jouanin
- Aviv Andriani
- Carolina Aguilera Galvez
- Xiao Lin
- Yerisf Torres Ascurra
- Xinfang Wang
- Thijs van Dijk
- Daniel Danial
- Angela Machacilla
- Bjarne Larsen
- Giorgio Tumino
- Reinhafd Simon