Natural products chemistry (dr. Teris A. van Beek)

Natural Products Chemistry is the science related to the investigation of naturally occurring substances that are characteristic for certain plant or animal species (secondary metabolites). Although it has strong foundations in analytical chemistry (chromatography) and synthetic chemistry, there are also often links to biological sciences (e.g., chemical ecology). The main interest in Wageningen was and is on modern analytical aspects of natural products: improvement of their isolation, purification, quantification and fast detection as well as quality control of natural extracts.

Current research interests
  • Ambient mass spectrometry
  • Quality control of essential oils
  • Gingko biloba
Current group members
Teris van Beek is gradually retiring and therefore slowly ending his research activities. There are no longer additional group members.
Teris van Beek studied pharmacy in Leiden, The Netherlands and afterwards obtained his PhD at the same university under supervision of Rob Verpoorte. In 1985 he joined Wageningen University, first as an assistant professor and from 1992 as an associate professor in the fields of phytochemistry, chemical ecology and natural products chemistry. During his time in Wageningen, he was involved in numerous projects carried out by PhD students (vide infra), MSc students, post-docs and/or technicians. In 1994-95 he spent a sabbatical at Virginia Tech on SFE/SFC under supervision of Larry Taylor. In 2000, he won the Phytochemical Society of Europe Award. Over the years, he cooperated with other research groups in Bulgaria, Canada, China, Czech Republic, Egypt, England, France, Germany, Greece, Italy, Japan, Lithuania, Nepal, the Netherlands, South Africa, Spain, Sweden and USA.
Former PhD students
Anton Blaakmeer, Maarten van Helden, Frans Griepink, Airidas Dapkevicius, Dorien Derksen, Jeroen van den Boezem, Irina Koleva, Cindy van den Boom, Falko Drijfhout, Audrius Pukalskas, Agnes Galimard, Frederique van Holthoon, Giedrius Miliauskas, Suzanne Jeurissen, Mercedes Pérez-Bonilla, Kishore Tetala, Tuha Vong, Radostina Manova, Yao Shen, Florine Duval, Dani Lucas-Barbosa, Wilco Duvivier, Sweccha Joshi and Alexandre Villela.
Publication list
Detailed publication & citation information is available via:
Linked-in (registration required):


224.  T.A. van Beek and D. Joulain, The essential oil of patchouli, Pogostemon cablin: A review, Flavour and Fragrance Journal, in press (1-46) (2018) DOI: 10.1002/ffj.3418 (open access)


223.  S. Joshi, H. Zuilhof, T.A. van Beek and M.W.F. Nielen, Biochip spray: simplified coupling of surface plasmon resonance biosensing and mass spectrometry, Analytical Chemistry, 89, 1427-1432 (2017) DOI: 10.1021/acs.analchem.6b04012

222.  D. Lucas-Barbosa, M. Dicke, T. Kranenburg, Y. Aartsma, T.A. van Beek, M.E. Huigens and J.J.A. van Loon, Seed set of mustard plants is reduced in the absence of natural enemies of herbivores, Functional Ecology, 31, 325-333 (2017) DOI: 10.1111/1365-2435.12756


221.  S. Joshi, R. Annida, H. Zuilhof, T.A. van Beek and M.W.F. Nielen, Analysis of mycotoxins in beer using a portable nanostructured imaging surface plasmon resonance biosensor, Journal of Agricultural and Food Chemistry, 64, 8263-8271 (2016) DOI: 10.1021/acs.jafc.6b04106

220.  M. Navarro-Reig, J. Jaumot, T.A. van Beek, G. Vivó-Truyols, R. Tauler, Chemometric analysis of comprehensive LC×LC-MS data: resolution of triacylglycerol structural isomers in corn oil, Talanta, 60, 624-635 (2016)  DOI: 10.1016/j.talanta.2016.08.005215.

219.  W.F. Duvivier, T.A. van Beek and M.W.F. Nielen, Critical comparison of mass analyzers for forensic hair analysis by ambient ionization mass spectrometry, Rapid Communications in Mass Spectrometry, 30, 2331-2340 (2016) DOI:  10.1002/rcm.7722

218.  D. Lucas-Barbosa, P. Sun, A. Hakman, T.A. van Beek, J.J.A. van Loon and M. Dicke, Visual and odour cues: plant responses to pollination and herbivory affect the behaviour of flower visitors, Functional Ecology, 30, 431-441 (2016) DOI: 10.1111/1365-2435.12509

217.  W.F. Duvivier, R.J.P. Peeters, T.A. van Beek and M.W.F. Nielen, Evidence based decontamination protocols for the removal of external D9-tetrahydrocannabinol (THC) from contaminated hair, Forensic Science International, 259, 110-118 (2016) DOI: 10.1016/j.forsciint.2015.12.014

216.  W.F. Duvivier, M.R. van Putten, T.A. van Beek and M.W.F. Nielen, (Un)targeted scanning of locks of hair for drugs of abuse by direct analysis in real time−high-resolution mass spectrometry, Analytical Chemistry, 88, 2489-2496 (2016)
DOI: 10.1021/acs.analchem.5b04759

215.  S. Joshi, A. Segarra-Fas, L. Sanchez Lopez, J. Peters, H. Zuilhof, T.A. van Beek and M.W.F. Nielen, Multiplex surface plasmon resonance biosensing and its transferability towards imaging nanoplasmonics for detection of mycotoxins in barley, Analyst, 141, 1307-1318 (2016)  DOI: 10.1039/c5an02512e


214.  S. Joshi, P. Pellacani, T.A. van Beek, H. Zuilhof, M.W.F. Nielen, Surface characterization and antifouling properties of nanostructured gold chips for imaging surface plasmon resonance biosensing, Sensors & Actuators: B. Chemical, 209, 505-514 (2015) DOI: 10.1016/j.snb.2014.11.133

213.  F. Duval, P. Wardani, H. Zuilhof and T.A. van Beek, Selective on-line detection of boronic acids and derivatives in High-Performance Liquid Chromatography eluates by post-column reaction with alizarin, Journal of Chromatography A, 1417, 57-63 (2015)   
DOI: j.chroma.2015.09.031

212.  W.F. Duvivier, T.A. van Beek, T. Meijer, R.J.P. Peeters, M.J. Groot, S.S. Sterk, M.W.F. Nielen, Ultra-trace LC-MS/MS analysis of segmented calf hair for retrospective assessment of time of clenbuterol administration in agriforensics, Journal of Agriculture and Food Chemistry, 63, 493-499 (2015)      DOI: 10.1021/jf5056437

211.  Y. Shen, T.A. van Beek, B. Chen, Alternative solvents can make preparative liquid chromatography greener, Green Chemistry, 17, 4073-4081 (2015)  DOI: 10.1039/c5gc00887e

210.  F. Duval, T.A. van Beek and H. Zuilhof, Key steps towards the oriented immobilization of antibodies using boronic acids, Analyst, 140, 6467-6472 (2015)    DOI:10.1039/c5an00589b