Wageningen Light Microscopy Centre

Good to know
In short- Confocal and TIRF systems
- Live-cell imaging
- Sample preparation
- Data storage and analysis
- Free training
The Wageningen Light Microscopy Centre (WLMC) offers companies and research organisations access to advanced light microscopy, including support with sample preparation, imaging and data analysis. By collaborating with WLMC, you obtain reliable, quantitative image data that allow you to accurately assess cellular processes and accelerate progress in your research.
What can you do at the Wageningen Light Microscopy Centre?
WLMC supports the full microscopy workflow of your research, from experimental design and sample preparation to high-quality imaging and data analysis. Our specialists help you select the right techniques and settings, ensuring images with a high signal-to-noise ratio and minimal artefacts.
The facility offers a broad range of light microscopes, including confocal systems (both point-scanning and spinning-disc), in upright and inverted configurations. Both horizontal and vertical sample positioning are possible. In addition to extensive sample preparation options, such as cryo-microtomy and vibratome sectioning, laser microdissection and micro-manipulation are also available.
Through temperature and gas regulation or the use of microfluidic sample chambers, dynamic processes in living cells can be recorded in time series with minimal artefacts. This enables visualisation of biological structures, materials, tissues, micro-organisms and food products, ranging from macro-scale overviews to sub-micrometre detail.
You receive training to work independently with the equipment. Reservation and access are arranged via WUR’s central booking system.
WLMC is equipped with, among others:
- Leica Stellaris 5 confocal LSM with White Light Laser
- Zeiss LSM 900 with horizontal and vertical imaging and AI-based image recognition
- Zeiss LSM 710 with water-dipping objective
- Leica SP8 confocal microscope
- Spinning-disc confocal microscope (Andor–Nikon Ti) with 5% CO₂ and temperature control
- Spinning-disc confocal microscope (Roper–Nikon Ti) combined with laser ablation
- Leica LMD7000 laser microdissection system
- Nikon 80i upright research microscope
- Zeiss Discovery V12 stereo microscope
- Inverted microscope with Hoffman Modulation Contrast and microinjection
- Cryo-microtome, vibratome and microtomes (3–300 µm)
Who is the Wageningen Light Microscopy Centre for?
WLMC is available to all WUR staff, as well as knowledge institutes and companies that require high-end imaging, for example in plant sciences, seed breeding, biotechnology, food, pharmaceuticals, materials research and marine biology. The facility also supports start-ups and SMEs.
Why choose this facility?

We offer:
- State-of-the-art microscopes
- Specialist support for design and preparation
- Quantitative image acquisition and analysis
- Secure storage and exchange of image data
- Cost-covering rates and free training
Questions about this facility?
Would you like more information? Please contact us.
dr.ing. NCA (Norbert) de Ruijter
Manager of the Wageningen Light Microscopy Centre