Immune cell dynamics
Customisable nanoparticles show great potential for imaging and advanced personalised medicine applications, such as cell therapies, immunomodulation, and cell tracking studies using multimodal imaging. Prof. Mangala Srinivas’ group works with a range of imaging modalities, incl. fluorescence, MRI, PET, SPECT, ultrasound and photoacoustic imaging in different disease models, particularly cancer and cardiovascular diseases.
Next to chemical signals, physical cues govern immune cell functioning. Daan Vorselen’s group focuses on mechanobiology and subcellular dynamics of immune cells. We use high-resolution (fluorescence) microscopy, molecular biology approaches and develop new biophysical approaches, such as deformable microparticles that act both as cellular mimics and force sensors. We specifically focus on the influence of physical forces on immune cell behavior. For more information on this research see: https://vorselenlab.com/
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prof.dr. M (Mangala) Srinivas
Professor/Chairholder
Research themes
(Food) allergy
At CBI we investigate the immunological mechanisms of allergy, the effect of food processing on food allergy, as well as cross-reactive allergies between known allergens and (novel) food proteins
Immunomodulation by food and feed
We focus on immunomodulatory effects of food and feed-components, as well as mucosal immunology projects, focussing on immune function in the gastrointestinal and respiratory tract.
Veterinary immunology
Veterinary immunology is the cornerstone of animal health and welfare, food security, and public health. Within CBI we study the function of immune cells in livestock and companion animals.
Immune cell dynamics
CBI works with a range of imaging modalities, incl. fluorescence, MRI, PET, SPECT, ultrasound and photoacoustic imaging in different disease models, particularly cancer and cardiovascular diseases.
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