Complex cell systems in animal disease research

About this expertise
In short- 3D cell models
- Studying host–pathogen interactions
- Reducing animal testing
- Translational models for vaccines and therapies
Complex cell systems, such as organoids, are miniature, self-organising versions of animal tissues and organs. Within the Bioveterinary Research domain, we develop and apply these advanced models to study animal diseases, test interventions and reduce the need for animal testing. By integrating life-like models with scientific expertise, we accelerate innovation in animal health and contribute to a more sustainable future.
Complex cell systems (CCS) – including organoids and organ-on-chip platforms – represent a breakthrough in animal health research. These 3D models closely mimic the structure and function of real tissues, providing a unique window into biological processes. They enable researchers to study host–pathogen interactions, immune responses and therapeutic effects in a highly controlled environment.
We develop organoids derived from pig, bovine and other animal tissues, such as respiratory organoids, to study viral infections and test therapies. Models for muscles, neurons and intestines are also under development, offering new ways to explore disease mechanisms, evaluate vaccines and improve diagnostics.
By replacing or refining animal testing, CCS models drive scientific innovation while supporting animal welfare and One Health strategies. They bridge the gap between laboratory and real-world conditions – paving the way for healthier, more resilient animals and safer food systems.
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For more information about the development and use of complex cell systems to fight animal diseases, contact our expert.
dr. RL (Rik) de Swart
Researcher Complex Cell systems