Project
Evaluation of genetic diversity
Determination and evaluation of genetic diversity within livestock breeds is of crucial importance for making the right conservation decisions and for an efficient use of resources available for conservation.
This project has the general objective of exploring the opportunities of large amounts of marker data for conservation of genetic diversity within livestock breeds. The recent availability of dense marker maps (SNP markers) for livestock species enables the evaluation of diversity for specific regions of the genome, and genetic diversity for specific traits at different regions at the genome can be localized.
The aims in this study are:
- develop scientific methods to evaluate genetic diversity across the whole genome using dense marker maps
- apply these methods to case studies, with focus on the neutral diversity over the genome and the diversity of specific traits, and the effect of selection
- translate the results into tools for the genetic conservation of livestock in gene banks
Publicaties
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An improved vitrification protocol for equine immature oocytes, resulting in a first live foal
Equine Veterinary Journal 50 (2018)3. - ISSN 0425-1644 - p. 391 - 397. -
Assessing the value of the Dutch Holstein-Friesian germplasm collection
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Begin is gemaakt met gesekst sperma bij varkens
Begin is gemaakt met gesekst sperma bij varkens, De Boerderij, 2019-01-09, Rene Stevens, https://www.boerderij.nl/Varkenshouderij/Achtergrond/2019/1/Begin-is-gemaakt-met-gesekst-sperma-bij-varkens-378641E/ -
Characterization of genetic diversity conserved in the gene bank for dutch cattle breeds
Diversity 11 (2019)12. - ISSN 1424-2818 - p. 1 - 13. -
Conservation priorities for the different lines of Dutch Red and White Friesian cattle change when relationships with other breeds are taken into account
Journal of Animal Breeding and Genetics 134 (2017)1. - ISSN 0931-2668 - p. 69 - 77. -
Conserving a single gene versus overall genetic diversity with the help of optimal contributions
In: Book of Abstracts of the 63rd Annual Meeting of the European Association for Animal Production. - : Wageningen Academic Publishers - ISBN 9789086867615 - p. 11 - 11. -
Cryobiology and Reproduction; Basic principles, recent advances
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Cryoconservation of animal genetic resources in europe and two African countries: A gap analysis
Diversity 11 (2019)12. - ISSN 1424-2818 - 11 p. -
Cryopreservation of avian semen
In: Cryopreservation and Freeze-Drying Protocols / , Wolkers, Willem F., Oldenhof, Hariëtte. - : Humana Press Inc. (Methods in Molecular Biology ) - ISBN 9781071607824 - p. 379 - 399. -
Cryopreservation of equine oocytes: Looking into the crystal ball
Reproduction Fertility and Development 32 (2020)5. - ISSN 1031-3613 - p. 453 - 467.