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Projects - prof.dr. J (John) van der Oost

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  ‘CARFing’ out the signalling network of CRISPR-Cas

  CRISPR are prokaryotic immune systems associated with nucleic acid degradation. Here, we explore a newly discovered CRISPR-associated signalling...
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  CRISPR-Enhanced: Towards better genome editing nucleases by directed evolution

  Guided nucleases have revolutionized the field for genetic engineering. Through directed evolution, we aim to improve modern genome engineering...
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  Seizing cell cycle of a synthetic cell

  The perspective of a synthetic cell makes it possible to rewrite the rules governing life. This project focuses on the cell cycle, aiming at designing...