Rinderpest virus (RPV), a member of genus Morbillivirus in the family Paramyxoviridae, causes an acute and often fatal disease in cattle and other large ruminants (buffalo and wild cloven-footed animals). Wageningen Bioveterinary Research conducts research on this disease.

No more rinderpest

After intensive and long-lasting vaccination campaigns, the world is declared free of rinderpest since 2011.

Clinical signs

Transmission takes place by direct or close indirect contacts. Rinderpest disease is characterized by high fever, discharge from eyes and nose, salivation, erosions of the mouth, gums and other mucous membranes, diarrhea, and dehydration.

Death is common, either from the disease itself or from secondary infections that are able to take advantage of the profound immunosuppression caused by a rinderpest virus infection.

Dreaded cattle disease

Rinderpest was considered until recently as the most dreaded cattle disease, causing massive losses of livestock and wildlife on three continents. The economic consequences of outbreaks of rinderpest in domestic livestock can be devastating.