Microbial and Genome Evolution & Dynamics in Eukaryotes
Within the working group of Microbial Evolution (MicEvo) we focus on exploring and characterizing the microbial diversity that exists on our planet. Moreover, we aim to explain how this diversity came about during billions of years of evolution.
To do this, we employ a variety of approaches, including cultivation-independent methods (e.g. metagenomics, comparative genomics, phylogenomics), but also novel cultivation-dependent methods (e.g. high-throughput cultivation and ecophysiology techniques).
Tree of Life
We are interested in relatively understudied branches in the Tree of Life, such as various archaeal lineages (e.g. Asgard and TACK archaea) and eukaryotic microorganisms ('protists'), but we also focus on various bacterial lineages (such as Alphaproteobacteria and Chlamydiae). Furthermore, we study how various microorganisms interact in microbial communities via symbiotic interactions. Of particular interest is an ancient symbiosis, between an ancient Asgard archaeon and proteobacterium, that gave rise to the first eukaryotic cell in a process referred to as ‘eukaryogenesis’.
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Research themes
Microbial and Synthetic Genetics & Metabolism
We study thermophilic bacteria and archaea, from their metabolism to CRISPR-Cas which defends them against viruses. In addition, we develop genome editing tools and optimise protein expression.
Microbial Evolution & Genome evolution and Dynamics in Eukaryotes
Within this theme, we focus on exploring and characterizing the microbial diversity that exists on our planet and how this diversity came about.
(Anaerobic) Microbial Physiology, Eukaryotes and interactions
To help create a sustainable circular economy, we investigate the physiology of the anaerobic microorganisms.
Complex Microbial Ecosystems & Marine Microbiology
Research and education within the Microbial Ecology Group aims to understand and explore the functioning of microorganisms in natural and man-made ecosystems, including interdependencies with their living and non-living environments.
Microbiome, Lumen & Diet, Mucus & Milk
Our research and education focus on ecological concepts of the intestinal microbiome in relation to diet and health.
Microbiology
The Laboratory of Microbiology, led by Thijs Ettema, engages in research and education focusing on fundamental and applied aspects of the diversity, physiology, ecology and evolution of microorganisms and their viruses.