Microbiome, Lumen & Diet, Mucus & Milk
Our research is focussed on the role of the microbiome in the intestine and how this is related to diet and health. We investigate, among others, intestinal microbes that are specialised in the degradation of dietary components, such as fibres, as well as host produced glycan rich proteins, including mucus & human milk components.
Key research issues include:
Research topics focus on innovative cultivation-based and molecular approaches aimed at understanding composition and functionality of the intestinal microbiome. Our research combines in vivo microbiological studies with human volunteers and underlying mechanistic in vitro studies using inocula derived from intestinal samples as well as synthetic consortia mimicking different parts of the intestine.
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Research themes
Microbial and Synthetic Genetics & Metabolism
We study thermophilic bacteria and archaea, from their metabolism to CRISPR-Cas which defends them against viruses. In addition, we develop genome editing tools and optimise protein expression.
Microbial Evolution & Genome evolution and Dynamics in Eukaryotes
Within this theme, we focus on exploring and characterizing the microbial diversity that exists on our planet and how this diversity came about.
(Anaerobic) Microbial Physiology, Eukaryotes and interactions
To help create a sustainable circular economy, we investigate the physiology of the anaerobic microorganisms.
Complex Microbial Ecosystems & Marine Microbiology
Research and education within the Microbial Ecology Group aims to understand and explore the functioning of microorganisms in natural and man-made ecosystems, including interdependencies with their living and non-living environments.
Microbiome, Lumen & Diet, Mucus & Milk
Our research and education focus on ecological concepts of the intestinal microbiome in relation to diet and health.
Microbiology
The Laboratory of Microbiology, led by Thijs Ettema, engages in research and education focusing on fundamental and applied aspects of the diversity, physiology, ecology and evolution of microorganisms and their viruses.