Antimicrobial resistance (AMR) in animals
About this expertise
In short- Diagnostics
- Surveillance
- Sequencing (including whole genome)
- Identifying AMR trends in livestock
Antimicrobial resistance (AMR) is one of the most pressing global health challenges of our time. It threatens the effectiveness of treatments in both animals and humans. Within the Bioveterinary Research domain, we study and monitor AMR in livestock to safeguard animal health, protect food systems and limit risks to public health. The researchers apply a One Health approach that connects animals, people and the environment.
As the National Reference Laboratory (NRL) for antibiotic resistance in animals, we play a key role in national monitoring. We maintain reference collections of bacterial strains, carry out benchmarking studies to harmonise resistance testing across veterinary diagnostic laboratories and advise governmental agencies on AMR policy and strategy.
We use advanced sequencing technologies such as whole genome sequencing (WGS) to map resistance genes (resistome analysis) and genotype resistant bacteria and plasmids. We also apply microarrays for gene detection and combine traditional sensitivity testing with risk assessment and modelling to better understand resistance dynamics.
Our research also focuses on microbiota as reservoirs of resistance genes. These genes are widely distributed among bacterial populations in the intestinal or respiratory microbiota, for example. Within these microbial communities, resistance genes can transfer between commensals and pathogens. By studying how interventions such as diet or probiotics affect these microbial ecosystems, we aim to limit the spread of resistant bacteria.
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For more information about reducing AMR and collaborating with us, contact our expert.
dr. KT (Kees) Veldman
Researcher Antimicrobial Resistance