Systems and Synthetic Biology
At the Systems and Synthetic Biology group, led by Maria Suarez Diez, we study the mechanisms underlying basic cellular processes, evolution and interactions among microbes and between microbes and their environment (including the human host). We do so in the context of entire biological systems. We translate the acquired knowledge into applications in biotechnological, medicine, and environmental science.
Research themes
Computational systems biology
We use mathematical models to study genomes of microbes as well as their functioning.
Systems health
In this theme, we aim to predict disease onset, progression, and remission by analysing patient data.
Semantic systems biology
We link biological data in such a way computers can better understand, combine, and use them in life sciences.
Microbial systems and synthetic biology
We develop novel technologies of DNA modification and genome engineering to re-design microbes for biotechnological application.
Education
Education by Systems and Synthetic Biology
The Laboratory of Systems and Synthetic Biology offers education via courses at the bachelor and master level of different study programmes along with challenge-based education. The Laboratory also participates in courses organised by other chair groups and in postgraduate courses. Additionally, the Laboratory offers a variety of BSc- and MSc-thesis projects, MSc Research practices, and facilitates and supervises internships.
Publications & Projects
Researchers of the Laboratory of Systems and Synthetic Biology publish on a regular basis in scientific journals, professional journals, scientific and popular books, and proceedings.
Highlighted publications
- A snapshot of biomanufacturing and the need for enabling research infrastructure
- Model-driven engineering of Cutaneotrichosporon oleaginosus ATCC 20509 for improved microbial oil production
- Towards a machine learning operations (MLOps) soft sensor for real-time predictions in industrial-scale fed-batch fermentation
Chair Holder
Maria Suarez Diez is the chair of Systems and Synthetic Biology. She develops mathematical models to help understand the dynamics of cellular networks. Her ultimate goal is to build a model that explains how communities of cells interact with each other and their surroundings; how they grow, adapt, and change.
She also has a clear vision for the work environment: “I want to create an environment where we all work together to achieve our goals, provide the best possible education and become the best versions of ourselves.”
prof.dr. M (Maria) Suarez Diez
Chair Holder
People of Systems and Synthetic Biology
Each chair group of Wageningen University & Research, under leadership of a professor, has its own area of expertise. Meet the people of Systems and Synthetic Biology.
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